Hypothermic myxedema coma erroneously diagnosed as myocardial infarction because of increased creatine kinase MB.
نویسندگان
چکیده
As is well recognized, activities of creatine kinase (CK, EC 2.7.3.2) and lactate dehydrogenase (EC 1.1.1.27) in plasma may be substantially increased in hypothyroidism. We emphasize here that an increase and decrease in CK-MB isoenzyme, characteristic of acute myocardial infarction, can occur in hypothermic myxedema coma without myocardial infarction.
منابع مشابه
Cardiac enzyme changes in myxedema coma.
A 74-year-old man with myxedema and hypothermia had increased activities in plasma of creatine kinase (CK; EC 2.7.3.2), aspartate aminotransferase (AST; EC 2.6.1.1), and lactate dehydrogenase (LD; EC 1.1.1.27) and increased proportions of CK-MB (up to 20% of total CK) and LD1 isoenzymes, but no clinical or investigational evidence of associated myocardial infarction. This case illustrates that ...
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عنوان ژورنال:
- Clinical chemistry
دوره 33 6 شماره
صفحات -
تاریخ انتشار 1987